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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0db511361251436c934afd1c14b7ebf229fabcb9ecf1cd9ea8b015d3e3e0d01' 
  AND token = 'JIfNpWep6co9OFstUB2Jy9Z+me/IiQ63GsvZKVBCMzo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}