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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48c2353da4aa3d025d26729d2fda91bed2198ee48f16dc3612addcc9a4f8cfb9' 
  AND token = 'kZmhIctIUfiX2NV/++RDf63BwTnRbcIHMCL/wtX2iYw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}