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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5430ea74452501e7d36e143bd9ae5b0b221a86a2a32083af5b1f7435f212bb51' 
  AND token = '2ZUhZ8TfVd1ptrt5c0oa+m03xLSiFadqPErAGGIRedw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}