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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cede1d72d1730d8e263c3c9c518865aebe82c925c9b9d301f9b744e962b6d82e' 
  AND token = '4EAxdOPq+JWAWiyQ8vI+fhiZSEWNjp3/coiyF/LZ2Ds=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}