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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06fee72d45619a2e5325e8df33ff9e9e15221303e81238473025b80abc161c52' 
  AND token = '4X+xZLihFEwu5xy1iWxxJsgyrZdUlhMdw0W5aO8+HvA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}