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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bee5e75d324df6cb4bb202d4d7517c02bc8143d26d89963ddb9bf066e7b003e8' 
  AND token = 'f/Uem+yK55PcBOlEyMHxSxlm9PTzp5cFSDkBHO7bgMo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}