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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5737d3d7e9a29fd5adea5abfb32c856b7a8a9cc6b99797dcdb8baf783f993b64' 
  AND token = 'jtfS6LMEbf3kniiV5/Qib380PPBl2dqBzX+DHnpPGg0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}