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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '186ca681ff72a94ec30db9aef7b950927ccb4aed6e173af5562c35a776a37994' 
  AND token = 'YuGnabZnMY4AOqYbWir1Uco2HCsfH0B/w25BLfTC2TY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}