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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2108a1b508235214bafb30e3e7467d3aabda4c8ab16b7ac6bd2ea902bd7486bf' 
  AND token = 'G32DQYrmIwPPa5vPWkbSs2hQ3SwbPnyd+jT8kcZIHog=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}