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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ec4aaa5d1ccdb679c1fc3385a13ae3449568e457622c527bbd2caddd5ab1eed' 
  AND token = '4LrF+SYhL90BgGhzZRw13EXVfWVZfanSVDfvoa86mw4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}