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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c0329442a96277dcaf90bdb26cc587d61c4f69852ca3d39f6ae2db6f8015e4a' 
  AND token = 'GhQT2hezcX/4p/MWLEdE48zudAi7gpPlRc8zBwMC+U8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}