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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ed302f7e3c86a37812a726f4dddef17d28031781ab611f2d9631230b9bcc82c' 
  AND token = 'uM+e1zL9F4TAIL4mKb5bzwqg+T0Z1woGmSCCbbbLj/g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}