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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e8d8a78e605059ba3ca47a62510aff9cd43cbb223d477f8af482ffdd07f49a6' 
  AND token = '4Yc8iSzpaIMfmxJ+udSmuwkJRdHhZTRagUK1y4doR8w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}