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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '646f21a236d205dcff61f05ffd9d6a35db9230fb3beed993f60c24fc3e9e0ed1' 
  AND token = 'RlgyEB7/QPz2Z/AH2cBKH14qQWsIX00Pwgck0w56wcM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}