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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8052206cd7872474dbd59faee7726c3d6e235d0199f2da5429bd0981521a5ba9' 
  AND token = 'bYDFKeSasc0GNz4EZj1X4CgyFqGgY92Rj6rN0Df3cAY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}