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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '58e6ea8da0747fea9448ed04221b133a5048061f295bbca125f3299fca3378d7' 
  AND token = '//cwp5iEBcjDb88KVsjFH0Qoj2tsAO+oMzvBEA8GI/o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}