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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd42a476e086f699f9fd78b2f01dffc1325486094401590f204d6d98959d0ffa7' 
  AND token = 'BO64BFeTlYlgv7b7sX/IKNL7ixZKKSeAF4Ny31s5cBc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}