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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52720ef78b3770a316d1e1b63c1372b9d3b6e1c2dd4f70a1e899b634bc1db660' 
  AND token = 'zpsH1Ye/zNxQyWKaX6OzIi7/Pi7TFmqYEbjrddg8+7I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}