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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd18566c4c94d80d9fc0f9d9b2cf43e310d9299ea0f54c0d3dc331c29b287c6e' 
  AND token = 'u4a2mx8MUwRG/hEIZmjGVxNoXHNa0fHFnjPci10g9bg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}