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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45a3bc1d73c278d2505bc648d6fbd2b6a0b452ae61a4a78b1c310a8ea1cd26de' 
  AND token = 'Nm799sTVG+Egil2PHEDudaga2Tk21SW4tBsLjuA0phw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}