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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ad42902db2230eb4c9559d10417b0c61263d7e5e46326676b03039b7d0e006b' 
  AND token = 'gXX6l0T1L8DrueBL3uX5lHbRg9MsD5PTP+Zk5wlz8T0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}