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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9075305f2378e58b6f236b6b3e4a3855023d69874b271b10d47ab59b1606f8d6' 
  AND token = 'frd5Rb2vfNQP3yyvCMpun4QGXxdBWzwzskIsvWV3DEg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}