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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e4de2118b03c428754a677ee8f5d180662609f9f5bf3a8f3e37a0c11964691f' 
  AND token = 'GYgf9r1DiN2YxHMsL/TSn80d9V5L73y1WMSg39ZUCLs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}