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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c87de02a2e7af31b23ba693d9807f33f121dfc2f910cbc8276be995aeefe921' 
  AND token = '0myNs8sG3zL5By3aXhjj4BfxXoYi3B5QQwHjKxK2t8U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}