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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1bee7ad650c5f9f156cbd2352deff1f73476f1cd72b69fc983f89b1d8bea329c' 
  AND token = '2aFg4yGe095822MoYIv5K8xY8UY2R49wq22lrR5LOLo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}