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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48b78e9c0ab4e763d0b6fb287b973db7fd93065a243fe36cd45ba9fce95a63ce' 
  AND token = 'pYwqkeGmvKjV0O9jcqcW/jWMxCGy2wZrjWC1DoV97OI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}