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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b5c2a0ae7b5eaa2b42cdebaea2920dc8a385351a68d92b944bf7b926e984134' 
  AND token = '+TpAoDWSoNE2DNzRvHM+2NDJ7IQmTXzjRIb7bYcDlTM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}