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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '615bf6c3f834e379ed13989e6960e61dff16a7504c14b55e66b1a658b004baaf' 
  AND token = 'xwssdmpTVuYWtXmMLEA+I0MsAN6n1N0tZYbEGSqsY0I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}