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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af6a5aa47b57525b14a4a480ad1c6f2927b63c9f826573014a6ce2ab07e18eb3' 
  AND token = 'Y4ZXjbCz+v9MQ6pS+UXV7ZsAfg3Vwb5KFZ7Rybbp1c8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}