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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '203a342667be283fa8cdf7a74e3c43089812e0421456ea434e4f25b70f350c7f' 
  AND token = '+Uada0MdpitirsM/MNyoFypN0MnHaNb8XVnOXYpaO4o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}