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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a24976b7b58fb060c9b4e7bdde1a23951db88f9cc1c4d0eb24cdd1255c042d16' 
  AND token = 'lPZp3442yNuw0ruFMS2r0IbJ+t0138oGUGHNrF2zAd4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}