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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2a4f79aa3122d48f130d7f61dbd0c882703e4a98f5f4bf832dce0e6a2da7b61' 
  AND token = 'xKHGG1kk6/h3dUBiEXYlY1BD66mI37DludrP6GgcWh8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}