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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dfe21e6739417308bb31e6758e82f5726ebbb18140a7ce2ec50cec30372c0fb5' 
  AND token = 'P1EoXYEbfWQTupY04emGih61fgHEVqM7FNWbU22oNJg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}