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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd49c8c7961aa3aee56dd5bd35ff92529a5955c5e2666d31c4a8f65188c8f780e' 
  AND token = 'yacVkK+1g/oYjzOrN5cOfJTXP4+9Qlxe3g1VIcQcHF4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}