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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f3263feb75a6922ec6c3b2dc082b233a37983fb3e10e2a5f9c422a6d614c597' 
  AND token = 'Eojo/uvYZGNISWW/041icIrs25gq6vXA6tgAJtVPVtc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}