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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd76e04974b87c65fa05cc7a3bf2f69df5fc1d40c38c7261922abce32c08d4715' 
  AND token = '5uSmBrRZj33WiTmef2CgI1FjsQfbZmtP9YPg5Na4L5Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}