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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b78a2a8938975cb1159959983c39033c55dc7082e2c52464ec680644107ea1d3' 
  AND token = '7i613DF5GhKV8ofm2J90MKM7BmbB8pYiXzhlTnrcMTA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}