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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5406a947a4791ff1e9554c591d25732082adabc2ea10c44bf5e019079a419266' 
  AND token = 'r+RqWxh9WDPtt4IzvUH/aTGUbIoqRaPPDcqyesgsHOI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}