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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '161875308a1f7951d48f16f7c1be6eead3a4a5c847242f369b5d273e9d7d656e' 
  AND token = 'o20gMe5TG3t+dbe8drT00dYjAgwQCSlznnSxi0wzdFU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}