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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6884b686dfce6b1171402f9733b3cd51e98bf3dafb7e60a2d9838d90f02f11be' 
  AND token = 'kbR7tXLQ0WKDvHVwm3c+3Vqfa5oiae+DD61yb2MuAig=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}