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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '90398c46c7e3c7a66bd2167e25fb82cd4f3e491fca336abba0171c28991b44c4' 
  AND token = 'e6TvZL0YwDVuv0nH2LGGTHWOrGrQE1MEQhNV2mJu66c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}