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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e71e428397f7e3adf170b5be290b9938b14a0fa004d964816e8715e2b2e4c37' 
  AND token = 'JkcUm0e6jipTeru3xWMfcUtJn1OoMv8DPdoVr0rk2fE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}