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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72d78a75ba6bf39b4dfb8f8f90e689d244ffe32f781a6885f33163e20befa7b6' 
  AND token = '5K839OS1boB0n1vvXnGrRypSno6iMcTppJZTRyUwiyA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}