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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8fb56f8a9834d11d7201e6070a90846e656a54564b8f52042f1223edbe1b758' 
  AND token = 'tjQ1bU1NfQNPscx2u5M1IW22NcgaLcfrjytuEnBWhZw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}