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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b8160baea452db4a90351b652a648f42f2a60bed323f4faeb5d41f4a3003d9c' 
  AND token = 'TyD/0vSqbQsEzU5eXhn9+V8hN2+h4e89IPO9Ax34k94=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}