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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80f427ff7cad696bfd933a0c11b078761d4334c7d08c8ecd8f61024c12c2fd00' 
  AND token = '18taP0xm3sYfA7vGb+3GgD1twykKiyZXNfc+Xh/D99E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}