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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8107e41142f449b9c76de44321684f5226a775e62a887c6c8828cb7e06aa8a6' 
  AND token = 'PnXUE0/TQHS1HojKjKjOWAgYkmtABtpQCJFwNda6sQc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}