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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40eb55ee69a6febd603a9bf349e6d08a1dbcc0d46f24bba18a002d8025585e35' 
  AND token = '5u2DXmyBMpgvULUbuRasEAmS3dUW2XxNElpIGu1ibyg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}