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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29f8a3ea2720e5be7a1715b20940f39eefc865eabb0e473e00a53ad51e9e9720' 
  AND token = 'IxCbL/SPaqkk8PRfODvByn54zmEKdPUeW377Fo/Qu3c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}