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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f305f6eeb193f2b4504473e7b17623d7bded745b223fc331dde577675560290f' 
  AND token = '2Vm0kBhcTgk1mMvBAJjg2uqidtvM+3TY/yvseHrsjyg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}